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Anti-DYN1 (Phospho-Ser778) Antibody

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产品名称: Anti-DYN1 (Phospho-Ser778) Antibody
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Anti-DYN1 (Phospho-Ser778) Antibody


Anti-DYN1 (Phospho-Ser778) Antibody  的详细介绍
Name: Anti-DYN1 (Phospho-Ser778) Antibody
See all DYN1 primary antibodies
Description: Rabbit polyclonal antibody to DYN1 (Phospho-Ser778)
Specificity: The antibody detects endogenous levels of DYN1 only when phosphorylated at serine 778.
Applications: WB
Reactivity: Human, Mouse, Rat
Immunogen: Peptide sequence around phosphorylation site of serine 778 (T-S-S(p)-P-T) derived from Human DYN1.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Concentration: 1.0mg / ml
Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20˚C
Function: Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.
Involvement in Disease: Epileptic encephalopathy, early infantile, 31: A form of epileptic encephalopathy, a heterogeneous group of severe childhood onset epilepsies characterized by refractory seizures, neurodevelopmental impairment, and poor prognosis. Development is normal prior to seizure onset, after which cognitive and motor delays become apparent.
Sequence Similarities: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
Cellular Location: Cytoplasm. Cytoplasm > Cytoskeleton.

Microtubule-associated.
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