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Anti-DUSP4 Antibody

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产品名称: Anti-DUSP4 Antibody
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简单介绍

Anti-DUSP4 Antibody


Anti-DUSP4 Antibody  的详细介绍
Name: Anti-DUSP4 Antibody
See all DUSP4 primary antibodies
Description: Rabbit polyclonal antibody to DUSP4
Specificity: The antibody detects endogenous level of total DUSP4 protein.
Applications: E, WB, IHC
Dilutions: ELISA: 1:1000-1:5000 Western blotting: 1:500-1:2000 Immunohistochemistry: 1:50-1:150
Reactivity: Human, Mouse
Immunogen: Fusion protein corresponding to a region derived from 197-394 amino acids of human dual specificity phosphatase 4
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Predicted MW: 43kd
Formulation: Supplied at 1.2mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.
Storage: Store at -20?C / 1 year
Function: Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.
Sequence Similarities: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Post-Translational Modification: Phosphorylation in the C-terminus by ERK1/2 inhibits proteasomal degradation and stabilizes the protein.
Cellular Location: Nucleus.
Database Links:
  • Entrez Gene: 1846?Human
  • Entrez Gene: 319520?Mouse
  • Omim: 602747?Human
  • SwissProt: Q13115?Human
  • SwissProt: Q8BFV3?Mouse
  • Unigene: 417962?Human
  • Unigene: 170276?Mouse
  • Unigene: 392187?Mouse
    		•
    Synonyms:
  • Dual specificity phosphatase 4 Antibody
  • Dual specificity protein phosphatase 4 Antibody
  • Dual specificity protein phosphatase hVH2 Antibody
  • DUS4_HUMAN Antibody
  • DUSP 4 Antibody
  • DUSP4 Antibody
  • HVH 2 Antibody
  • HVH2 Antibody
  • MAP kinase phosphatase 2 Antibody
  • Mitogen activated protein kinase phosphatase 2 Antibody
  • Mitogen-activated protein kinase phosphatase 2 Antibody
  • MKP 2 Antibody
  • MKP-2 Antibody
  • MKP2 Antibody
  • Serine/threonine specific protein phosphatase Antibody
  • TYP Antibody
  • Typ1 Antibody
  • VH 2 Antibody
  • VH1 homologous phosphatase 2 Antibody
  • VH2 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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