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Anti-DUSP16 Antibody

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产品名称: Anti-DUSP16 Antibody
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简单介绍

Anti-DUSP16 Antibody


Anti-DUSP16 Antibody  的详细介绍
Name: Anti-DUSP16 Antibody
See all DUSP16 primary antibodies
Description: Goat polyclonal antibody to DUSP16.
Applications: ELISA, IHC
Reactivity: Human
Immunogen: Synthetic peptide corresponding to Human DUSP16 (N terminal).
Sequence: AHEMIGTQIVTER-C
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 μg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2.
Sequence Similarities: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Post-Translational Modification: Phosphorylated at Ser-446 by MAPK1/ERK2, which prevents its degradation, and thereby stabilizes it and blocks JNK MAPK activity.
Cellular Location: Cytoplasm. Nucleus. Cytoplasmic vesicle.

After dissociation upon AGTR stimulation, re-associates with ARRB2 on endocytic vesicles.
Database Links:
  • Entrez Gene: 80824?Human
  • Omim: 607175?Human
  • SwissProt: Q9BY84?Human
  • Unigene: 536535?Human
    		•
    Synonyms:
  • Dual specificity phosphatase 16 Antibody
  • Dual specificity protein phosphatase 16 Antibody
  • DUS16_HUMAN Antibody
  • DUSP 16 Antibody
  • DUSP16 Antibody
  • KIAA1700 Antibody
  • MAP kinase phosphatase 7 Antibody
  • MAPK phosphatase 7 Antibody
  • Mitogen activated protein kinase phosphatase 7 Antibody
  • Mitogen-activated protein kinase phosphatase 7 Antibody
  • MKP 7 Antibody
  • MKP-7 Antibody
  • MKP7 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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