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Anti-DSC2 Antibody

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产品名称: Anti-DSC2 Antibody
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Anti-DSC2 Antibody


Anti-DSC2 Antibody  的详细介绍
Name: Anti-DSC2 Antibody
See all DSC2 primary antibodies
Description: Rabbit polyclonal antibody to DSC2
Specificity: The antibody detects endogenous levels of total DSC2 protein.
Applications: IHC
Reactivity: Human
Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human desmocollin 2
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 2.3mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.
Tissue Specificity: Expressed in epithelia, myocardium and lymph nodes.
Involvement in Disease: Arrhythmogenic right ventricular dysplasia, familial, 11: A congenital heart disease characterized by infiltration of adipose and fibrous tissue into the right ventricle and loss of myocardial cells, resulting in ventricular and supraventricular arrhythmias.
Cellular Location: Cell membrane. Cell junction > Desmosome.
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