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Anti-DRD5 Antibody

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产品名称: Anti-DRD5 Antibody
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简单介绍

Anti-DRD5 Antibody


Anti-DRD5 Antibody  的详细介绍
Name: Anti-DRD5 Antibody
See all DRD5 primary antibodies
Description: Rabbit polyclonal antibody to DRD5
Specificity: DRD5 pAb detects endogenous levels of DRD5 protein.
Applications: WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant full length Human DRD5.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 53 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol.
Function: Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
Tissue Specificity: Neuron-specific, localized primarily within limbic regions of the brain.
Involvement in Disease: Benign essential blepharospasm: A primary focal dystonia affecting the orbicularis oculi muscles. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. BEB usually begins in middle age. Initial symptoms include eye irritation and frequent blinking, progressing to involuntary spasms of eyelid closure. Patients have normal eyes. The visual disturbance is due solely to the forced closure of the eyelids. In severe cases, this can lead to functional blindness.
Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.
Cellular Location: Cell membrane.
Database Links:
  • Entrez Gene: 1816?Human
  • Entrez Gene: 13492?Mouse
  • Entrez Gene: 25195?Rat
  • Omim: 126453?Human
  • SwissProt: P21918?Human
  • SwissProt: Q8BLD9?Mouse
  • SwissProt: P25115?Rat
  • Unigene: 380681?Human
  • Unigene: 167154?Mouse
  • Unigene: 138110?Rat
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    Synonyms:
  • D(1B) dopamine receptor Antibody
  • D(5) dopamine receptor Antibody
  • D1 beta dopamine receptor Antibody
  • D1B dopamine receptor Antibody
  • D1beta dopamine receptor Antibody
  • D5 dopamine receptor Antibody
  • DBDR Antibody
  • Dopamine D5 receptor Antibody
  • Dopamine receptor D1B Antibody
  • Dopamine Receptor D5 Antibody
  • DRD 1B Antibody
  • DRD 5 Antibody
  • DRD1B Antibody
  • DRD1L2 Antibody
  • DRD5 Antibody
  • DRD5_HUMAN Antibody
  • MGC10601 Antibody
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    Information: Target information shown above is from the UniProt Consortium.
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