产品资料

Anti-DRD3 Antibody

如果您对该产品感兴趣的话,可以
产品名称: Anti-DRD3 Antibody
产品型号:
产品展商: 其它品牌
产品文档: 无相关文档

简单介绍

Anti-DRD3 Antibody


Anti-DRD3 Antibody  的详细介绍
Name: Anti-DRD3 Antibody
See all DRD3 primary antibodies
Description: Rabbit polyclonal antibody to DRD3
Specificity: The antibody detects endogenous level of total DRD3 antibody.
Applications: WB, IF
Reactivity: Human
Immunogen: Recombinant protein of human DRD3.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antibodies were purified by affinity purification using immunogen.
Concentration: 1.0mg / ml
Formulation: Supplied at 1.0mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20˚C
Function: Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation.
Tissue Specificity: Brain.
Involvement in Disease: Tremor, hereditary essential 1: A common movement disorder mainly characterized by postural tremor of the arms. Head, legs, trunk, voice, jaw, and facial muscles also may be involved. The condition can be aggravated by emotions, hunger, fatigue and temperature extremes, and may cause a functional disability or even incapacitation. Inheritance is autosomal dominant.
Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.
Post-Translational Modification: Phosphorylated by GRK4 (GRK4-alpha and GRK4-gamma).
Cellular Location: Cell membrane.

Both membrane-bound and scattered in the cytoplasm during basal conditions. Receptor stimulation results in the rapid internalization and sequestration of the receptors at the perinuclear area (5 and 15 minutes), followed by the dispersal of the receptors to the membrane (30 minutes). DRD3 and GRK4 co-localize in lipid rafts of renal proximal tubule cells.
Database Links:
  • Entrez Gene: 1814 Human
  • Omim: 126451 Human
  • SwissProt: P35462 Human
  • Unigene: 121478 Human
    		•
    Synonyms:
  • 3dopamine receptor Antibody
  • D Antibody
  • D(3) dopamine receptor Antibody
  • Dopamine D3 receptor Antibody
  • Dopamine Receptor D3 Antibody
  • DRD3 Antibody
  • DRD3_HUMAN Antibody
  • ETM1 Antibody
  • FET1 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
    产品留言
    标题
    联系人
    联系电话
    内容
    验证码
    点击换一张
    注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
    2.如有必要,请您留下您的详细联系方式!

    沪公网安备 31011202007337号