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Anti-DR1 Antibody

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产品名称: Anti-DR1 Antibody
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简单介绍

Anti-DR1 Antibody


Anti-DR1 Antibody  的详细介绍
Name: Anti-DR1 Antibody
See all DR1 primary antibodies
Description: Rabbit polyclonal antibody to DR1.
Applications: WB, IHC
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200.
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human DR1.
Protein Length: 176
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Sequence Similarities: Belongs to the NC2 beta/DR1 family.
Post-Translational Modification: Phosphorylation regulates its interaction with TBP. Not phosphorylated when bound to DRAP1.
Cellular Location: Nucleus.
Database Links:
  • Entrez Gene: 1810?Human
  • Entrez Gene: 13486?Mouse
  • Entrez Gene: 289881?Rat
  • Omim: 601482?Human
  • SwissProt: Q01658?Human
  • SwissProt: Q91WV0?Mouse
  • SwissProt: Q5XI68?Rat
  • Unigene: 348418?Human
  • Unigene: 303534?Mouse
  • Unigene: 6666?Rat
    		•
    Synonyms:
  • Down regulator of transcription 1 Antibody
  • Down regulator of transcription 1 TBP binding Antibody
  • Down-regulator of transcription 1 Antibody
  • down-regulator of transcription 1, TBP-binding (negative cofactor 2) Antibody
  • DR 1 Antibody
  • DR1 Antibody
  • Dr1 protein Antibody
  • NC 2 Antibody
  • NC2 Antibody
  • NC2 beta Antibody
  • NC2-beta Antibody
  • NC2B_HUMAN Antibody
  • Negative co factor 2 Antibody
  • Negative cofactor 2 Antibody
  • Negative cofactor 2 beta Antibody
  • Negative cofactor 2-beta Antibody
  • Protein Dr1 Antibody
  • TATA binding protein associated phosphoprotein Antibody
  • TATA box/binding protein associated phosphoprotein DR1 Antibody
  • TATA-binding protein-associated phosphoprotein Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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