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Anti-DPYSL3 Antibody

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产品名称: Anti-DPYSL3 Antibody
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简单介绍

Anti-DPYSL3 Antibody


Anti-DPYSL3 Antibody  的详细介绍
Name: Anti-DPYSL3 Antibody
See all DPYSL3 primary antibodies
Description: Rabbit polyclonal antibody to DPYSL3
Specificity: The antibody detects endogenous levels of total DPYSL3 protein.
Applications: WB, IHC
Reactivity: Human, Mouse
Immunogen: Fusion protein corresponding to residues near the C terminal of human dihydropyrimidinase-like 3
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1.3mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity).
Tissue Specificity: Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord.
Sequence Similarities: Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
Post-Translational Modification: Phosphorylation on Ser-522 by DYRK2 promotes subsequent phosphorylation on Thr-509, Thr-514 and Ser-518 by GSK3.
Cellular Location: Cytoplasm. Cell projection > Growth cone.

Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.
Database Links:
  • Entrez Gene: 1809?Human
  • Entrez Gene: 22240?Mouse
  • Omim: 601168?Human
  • SwissProt: Q14195?Human
  • SwissProt: Q62188?Mouse
  • Unigene: 519659?Human
  • Unigene: 428551?Mouse
  • Unigene: 8180?Mouse
    		•
    Synonyms:
  • Collapsin response mediator protein 4 Antibody
  • Collapsin response mediator protein 4 long Antibody
  • CRMP 4 Antibody
  • CRMP-4 Antibody
  • CRMP4 Antibody
  • Dihydropyrimidinase like 3 Antibody
  • Dihydropyrimidinase related protein 3 Antibody
  • Dihydropyrimidinase-related protein 3 Antibody
  • DPYL3_HUMAN Antibody
  • DPYSL3 Antibody
  • DRP 3 Antibody
  • DRP-3 Antibody
  • DRP3 Antibody
  • LCRMP Antibody
  • TUC4 Antibody
  • ULIP Antibody
  • ULIP 1 Antibody
  • ULIP-1 Antibody
  • ULIP1 Antibody
  • Unc 33 like phosphoprotein Antibody
  • UNc 33 like phosphoprotein 1 Antibody
  • Unc-33-like phosphoprotein 1 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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