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Anti-DOK6 Antibody

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产品名称: Anti-DOK6 Antibody
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简单介绍

Anti-DOK6 Antibody


Anti-DOK6 Antibody  的详细介绍
Name: Anti-DOK6 Antibody
See all DOK6 primary antibodies
Description: Rabbit polyclonal antibody to DOK6
Specificity: The antibody detects endogenous levels of total DOK6 protein.
Applications: WB, IF
Reactivity: Human, Mouse
Immunogen: Synthesized peptide derived from internal of human DOK6.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1.0mg / ml
Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20˚C
Function: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret-mediated neurite growth. May have a role in brain development and/or maintenance.
Tissue Specificity: Highly expressed in fetal and ***** brain. Highly expressed in the cerebellum. Weak expression in kidney, spinal cord and testis.
Sequence Similarities: Belongs to the DOK family. Type B subfamily.
Post-Translational Modification: On Ret activation, phosphorylated on one or more C-terminal tyrosine residues by an Src family kinase.
Database Links:
  • Entrez Gene: 220164 Human
  • Entrez Gene: 623279 Mouse
  • Omim: 611402 Human
  • SwissProt: Q6PKX4 Human
  • SwissProt: Q2MHE5 Mouse
    		•
    Synonyms:
  • Docking protein 5 Antibody
  • Docking protein 5 like Antibody
  • Docking protein 6 Antibody
  • DOK 6 Antibody
  • DOK5 Antibody
  • DOK5L Antibody
  • DOK6 Antibody
  • Downstream of tyrosine kinase 6 Antibody
  • HsT3226 Antibody
  • MGC20785 Antibody
  • Protein dok 5 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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