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Anti-DOK3 Antibody

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产品名称: Anti-DOK3 Antibody
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简单介绍

Anti-DOK3 Antibody


Anti-DOK3 Antibody  的详细介绍
Name: Anti-DOK3 Antibody
See all DOK3 primary antibodies
Description: Goat polyclonal antibody to DOK3.
Applications: ELISA, WB
Reactivity: Human
Immunogen: Synthetic peptide corresponding to Human DOK3 (C terminal).
Sequence: TRERRKGPAPCDRP
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 µg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function (By similarity).
Tissue Specificity: Expressed in spleen.
Sequence Similarities: Belongs to the DOK family. Type A subfamily.
Post-Translational Modification: Constitutively tyrosine-phosphorylated.
Cellular Location: Cytoplasm. Cell membrane.
Database Links:
  • Entrez Gene: 79930 Human
  • Omim: 611435 Human
  • SwissProt: Q7L591 Human
  • Unigene: 720849 Human
    		•
    Synonyms:
  • Docking protein 3 Antibody
  • DOK 3 Antibody
  • DOK Like Protein Antibody
  • DOK3 Antibody
  • DOK3_HUMAN Antibody
  • DOKL Pending Antibody
  • Downstream of tyrosine kinase 3 Antibody
  • p62 DOK Like Protein Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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