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Anti-Dok-6 (G130) Antibody

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产品名称: Anti-Dok-6 (G130) Antibody
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Anti-Dok-6 (G130) Antibody


Anti-Dok-6 (G130) Antibody  的详细介绍
Name: Anti-Dok-6 (G130) Antibody
See all Dok6 primary antibodies
Description: Rabbit polyclonal antibody to Dok-6 (G130)
Specificity: Dok-6 (G130) pAb detects endogenous levels of Dok-6 protein.
Applications: WB, IHC, IF
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 98-149 of Human Dok-6.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 43 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Function: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret-mediated neurite growth. May have a role in brain development and/or maintenance.
Tissue Specificity: Highly expressed in fetal and ***** brain. Highly expressed in the cerebellum. Weak expression in kidney, spinal cord and testis.
Sequence Similarities: Belongs to the DOK family. Type B subfamily.
Post-Translational Modification: On Ret activation, phosphorylated on one or more C-terminal tyrosine residues by an Src family kinase.
Database Links:
  • Entrez Gene: 220164?Human
  • Entrez Gene: 623279?Mouse
  • Entrez Gene: 498898?Rat
  • Omim: 611402?Human
  • SwissProt: Q6PKX4?Human
  • SwissProt: Q2MHE5?Mouse
    		•
    Synonyms:
  • Docking protein 5 Antibody
  • Docking protein 5 like Antibody
  • Docking protein 6 Antibody
  • DOK 6 Antibody
  • DOK5 Antibody
  • DOK5L Antibody
  • DOK6 Antibody
  • Downstream of tyrosine kinase 6 Antibody
  • HsT3226 Antibody
  • MGC20785 Antibody
  • Protein dok 5 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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