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Anti-DNAJA1 Antibody

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产品名称: Anti-DNAJA1 Antibody
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Anti-DNAJA1 Antibody


Anti-DNAJA1 Antibody  的详细介绍
Name: Anti-DNAJA1 Antibody
See all DNAJA1 primary antibodies
Description: Rabbit polyclonal antibody to DNAJA1
Specificity: The antibody detects endogenous levels of total DNAJA1 protein.
Applications: WB, IHC
Reactivity: Human
Immunogen: Fusion protein corresponding to a region derived from internal residues of human DnaJ (Hsp40) homolog, subfamily A, member 1
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 2.8mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Co-chaperone for HSPA8/Hsc70 (PubMed:10816573). Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro) (PubMed:24318877). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis (PubMed:14752510). Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV (PubMed:24512202).
Tissue Specificity: Ubiquitous. Isoform 2 is highly expressed in testis and lung, but detected at low levels in thymus, prostate, colon and liver.
Cellular Location: Membrane. Cytoplasm. Microsome. Nucleus. Cytoplasm > Perinuclear region. Mitochondrion.

Primarily associated with microsomes. A minor proportion is associated with mitochondria (By similarity). Primarily cytoplasmic. A minor proportion is associated with nuclei.
Database Links:
  • Entrez Gene: 3301?Human
  • Omim: 602837?Human
  • SwissProt: P31689?Human
  • Unigene: 445203?Human
    		•
    Synonyms:
  • DJ 2 Antibody
  • DJ2 Antibody
  • DjA1 Antibody
  • DnaJ (Hsp40) homolog, subfamily A, member 1 Antibody
  • DnaJ homolog subfamily A member 1 Antibody
  • DnaJ protein homolog 2 Antibody
  • DNAJ2 Antibody
  • Dnaja1 Antibody
  • DNJA1_HUMAN Antibody
  • hDJ 2 Antibody
  • HDJ-2 Antibody
  • HDJ2 Antibody
  • Heat shock 40 kDa protein 4 Antibody
  • heat shock protein DNAJ like 2 Antibody
  • Heat shock protein J2 Antibody
  • HSDJ Antibody
  • HSJ-2 Antibody
  • HSJ2 Antibody
  • HSPF4 Antibody
  • Human DnaJ protein 2 Antibody
  • NEDD7 Antibody
  • Neural precursor cell expressed developmentally down regulated 7 Antibody
  • OTTHUMP00000021193 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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