产品资料

Anti-DKK4 Antibody

如果您对该产品感兴趣的话,可以
产品名称: Anti-DKK4 Antibody
产品型号:
产品展商: 其它品牌
产品文档: 无相关文档

简单介绍

Anti-DKK4 Antibody


Anti-DKK4 Antibody  的详细介绍
Name: Anti-DKK4 Antibody
See all DKK4 primary antibodies
Description: Goat polyclonal antibody to DKK4.
Applications: ELISA, WB
Reactivity: Human
Immunogen: Synthetic peptide corresponding to Human DKK4 (C terminal).
Sequence: RQHARLRVCQKIEKL
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 µg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the *****, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
Tissue Specificity: Expressed in cerebellum, T-cells, esophagus and lung.
Sequence Similarities: Belongs to the dickkopf family.
Post-Translational Modification: Appears to be not glycosylated.
Cellular Location: Secreted.
Database Links:
  • Entrez Gene: 27121 Human
  • GenBank: NP_055235.1 Human
  • Omim: 605417 Human
  • SwissProt: Q9UBT3 Human
  • Unigene: 159311 Human
    		•
    Synonyms:
  • Dickkopf 4 Antibody
  • Dickkopf gene 4 Antibody
  • Dickkopf homolog 4 Antibody
  • Dickkopf homolog 4 (Xenopus laevis) Antibody
  • Dickkopf related protein 4 Antibody
  • Dickkopf-4 Antibody
  • Dickkopf-related protein 4 short form Antibody
  • Dickkopf4 Antibody
  • DKK 4 Antibody
  • Dkk-4 Antibody
  • DKK4 Antibody
  • DKK4_HUMAN Antibody
  • hDkk 4 Antibody
  • hDkk-4 Antibody
  • hDkk4 Antibody
  • MGC129562 Antibody
  • MGC129563 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
    产品留言
    标题
    联系人
    联系电话
    内容
    验证码
    点击换一张
    注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
    2.如有必要,请您留下您的详细联系方式!

    沪公网安备 31011202007337号