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Anti-Dio-1 (S186) Antibody

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Anti-Dio-1 (S186) Antibody


Anti-Dio-1 (S186) Antibody  的详细介绍
Name: Anti-Dio-1 (S186) Antibody
See all Dio-1 primary antibodies
Description: Rabbit polyclonal antibody to Dio-1 (S186)
Specificity: Dio-1 (S186) pAb detects endogenous levels of Dio-1 protein.
Applications: WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 154-198 of Human Dio-1.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 244 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Function: Putative transcription factor, weakly pro-apoptotic when overexpressed (By similarity). Tumor suppressor. Required for early embryonic stem cell development.
Tissue Specificity: Ubiquitous.
Cellular Location: Cytoplasm. Nucleus. Cytoplasm > Cytoskeleton > Spindle.

Translocates to the nucleus after pro-apoptotic stimuli (By similarity). Translocates to the mitotic spindle upon loss of interaction with H3K4me3 during early mitosis.
Database Links:
  • Entrez Gene: 11083?Human
  • Entrez Gene: 23856?Mouse
  • Omim: 604140?Human
  • SwissProt: Q9BTC0?Human
  • SwissProt: Q8C9B9?Mouse
  • Unigene: 15783?Human
  • Unigene: 517172?Human
  • Unigene: 253836?Mouse
  • Unigene: 485484?Mouse
    		•
    Synonyms:
  • BYE 1 Antibody
  • BYE1 Antibody
  • C20orf158 Antibody
  • DATF 1 Antibody
  • DATF-1 Antibody
  • DATF1 Antibody
  • Death associated transcription factor 1 Antibody
  • Death inducer obliterator 1 Antibody
  • Death-associated transcription factor 1 Antibody
  • Death-inducer obliterator 1 Antibody
  • DIDO 1 Antibody
  • DIDO 2 Antibody
  • DIDO 3 Antibody
  • DIDO1 Antibody
  • DIDO1_HUMAN Antibody
  • DIDO2 Antibody
  • DIDO3 Antibody
  • DIO 1 Antibody
  • DIO-1 Antibody
  • DIO1 Antibody
  • dJ885L7.8 Antibody
  • DKFZp434P1115 Antibody
  • FLJ11265 Antibody
  • hDido 1 Antibody
  • hDido1 Antibody
  • KIAA0333 Antibody
  • MGC16140 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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