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Anti-DECR1 Antibody

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产品名称: Anti-DECR1 Antibody
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Anti-DECR1 Antibody


Anti-DECR1 Antibody  的详细介绍
Name: Anti-DECR1 Antibody
See all DECR1 primary antibodies
Description: Rabbit polyclonal antibody to DECR1
Specificity: The antibody detects endogenous levels of total DECR1 protein.
Applications: WB, IHC
Reactivity: Human
Immunogen: Synthetic peptide corresponding to residues near the C terminal of human 2,4-dienoyl CoA reductase 1, mitochondrial
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 3.2mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.
Tissue Specificity: Heart = liver = pancreas > kidney >> skeletal muscle = lung.
Involvement in Disease: 2,4-dienoyl-CoA reductase deficiency: A rare, autosomal recessive, inborn error of polyunsaturated fatty acids and lysine metabolism, resulting in mitochondrial dysfunction. Affected individuals have a severe encephalopathy with neurologic and metabolic abnormalities beginning in early infancy. Laboratory studies show increased C10:2 carnitine levels and hyperlysinemia.
Sequence Similarities: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.
Cellular Location: Mitochondrion.
Database Links:
  • Entrez Gene: 1666?Human
  • Omim: 222745?Human
  • SwissProt: Q16698?Human
  • Unigene: 492212?Human
    		•
    Synonyms:
  • 1200012F07Rik Antibody
  • 2 Antibody
  • 2,4 dienoyl CoA reductase 1 Antibody
  • 2,4 dienoyl CoA reductase mitochondrial Antibody
  • 2,4 dienoyl CoA reductase [NADPH] Antibody
  • 2,4-dienoyl-CoA reductase, mitochondrial Antibody
  • 4 enoyl CoA reductase Antibody
  • 4-dienoyl-CoA reductase [NADPH] Antibody
  • 4-enoyl-CoA reductase [NADPH] Antibody
  • DECR Antibody
  • DECR 1 Antibody
  • DECR1 Antibody
  • DECR_HUMAN Antibody
  • Nadph Antibody
  • OTTMUSP00000004962 Antibody
  • RP23-338J24.3 Antibody
  • SDR18C1 Antibody
  • Short chain dehydrogenase/reductase family 18C member 1 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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