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Anti-Dact2 Antibody

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产品名称: Anti-Dact2 Antibody
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简单介绍

Anti-Dact2 Antibody


Anti-Dact2 Antibody  的详细介绍
Name: Anti-Dact2 Antibody
See all Dact2 primary antibodies
Description: Rabbit polyclonal antibody to Dact2
Applications: E, WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Raised against a 12 amino acid peptide from near the amino terminus of human DACT2.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Affinity chromatography purified via peptide column
Formulation: Supplied in PBS containing 0.02% sodium azide.
Storage: Can be stored at -20?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Function: Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling.
Tissue Specificity: Expressed in kidney (inner medullary collecting duct). Expressed in epidermal keratinocytes and hair follicles.
Sequence Similarities: Belongs to the dapper family.
Database Links:
  • Entrez Gene: 168002?Human
  • Entrez Gene: 240025?Mouse
  • Entrez Gene: 308212?Rat
  • Omim: 608966?Human
  • SwissProt: Q5SW24?Human
  • SwissProt: Q7TN08?Mouse
  • Unigene: 673059?Human
  • Unigene: 79993?Mouse
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    Synonyms:
  • bA503C24.7 Antibody
  • C6orf116 Antibody
  • Chromosome 6 open reading frame 116 Antibody
  • Dact2 Antibody
  • DACT2_HUMAN Antibody
  • Dapper antagonist of beta catenin homolog 2 Antibody
  • Dapper antagonist of beta catenin homolog 2 Xenopus laevis Antibody
  • Dapper homolog 2 Antibody
  • Dapper homolog 2 antagonist of beta catenin Antibody
  • Dapper homolog 2 antagonist of beta catenin xenopus Antibody
  • DAPPER2 Antibody
  • DPR2 Antibody
  • FLJ31232 Antibody
  • MGC133141 Antibody
  • MGC133142 Antibody
  • RP11 503C24.7 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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