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Anti-D-3-phosphoglycerate dehydrogenase Antibody

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产品名称: Anti-D-3-phosphoglycerate dehydrogenase Antibody
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Anti-D-3-phosphoglycerate dehydrogenase Antibody


Anti-D-3-phosphoglycerate dehydrogenase Antibody  的详细介绍
Name: Anti-D-3-phosphoglycerate dehydrogenase Antibody
See all D-3-phosphoglycerate dehydrogenase primary antibodies
Description: Rabbit polyclonal antibody to D-3-phosphoglycerate dehydrogenase
Specificity: The antibody detects endogenous level of total D-3-phosphoglycerate dehydrogenase polyclonal antibody.
Applications: WB, IHC
Reactivity: Human
Immunogen: Recombinant human D-3-phosphoglycerate dehydrogenase protein
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Concentration: 1.0mg / mL
Formulation: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage: Store at -20?C
Function: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate.
Involvement in Disease: Phosphoglycerate dehydrogenase deficiency: An autosomal recessive inborn error of L-serine biosynthesis, clinically characterized by congenital microcephaly, psychomotor retardation, and seizures.

Neu-Laxova syndrome 1: A lethal, autosomal recessive multiple malformation syndrome characterized by ichthyosis, marked intrauterine growth restriction, microcephaly, short neck, limb deformities, hypoplastic lungs, edema, and central nervous system anomalies including lissencephaly, cerebellar hypoplasia and/or abnormal/agenesis of the corpus callosum. Abnormal facial features include severe proptosis with ectropion, hypertelorism, micrognathia, flattened nose, and malformed ears.
Sequence Similarities: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Database Links:
  • Entrez Gene: 26227?Human
  • Omim: 606879?Human
  • SwissProt: O43175?Human
  • Unigene: 487296?Human
    		•
    Synonyms:
  • 3 PGDH Antibody
  • 3-PGDH Antibody
  • 3-phosphoglycerate dehydrogenase Antibody
  • 3PGDH Antibody
  • D-3-phosphoglycerate dehydrogenase Antibody
  • EC 1.1.1.95 Antibody
  • Epididymis secretory protein Li 113 Antibody
  • HEL S 113 Antibody
  • NLS Antibody
  • NLS1 Antibody
  • PDG Antibody
  • PGAD Antibody
  • PGD Antibody
  • PGDH Antibody
  • PGDH3 Antibody
  • PHGDH Antibody
  • PHGDHD Antibody
  • Phosphoglycerate dehydrogenase Antibody
  • SERA Antibody
  • SERA_HUMAN Antibody
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    Information: Target information shown above is from the UniProt Consortium.
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