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Anti-Cytochrome P450 8B1 Antibody

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产品名称: Anti-Cytochrome P450 8B1 Antibody
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Anti-Cytochrome P450 8B1 Antibody


Anti-Cytochrome P450 8B1 Antibody  的详细介绍
Name: Anti-Cytochrome P450 8B1 Antibody
See all Cytochrome P450 8B1 primary antibodies
Description: Rabbit polyclonal antibody to Cytochrome P450 8B1
Specificity: The antibody detects endogenous levels of total Cytochrome P450 8B1 protein.
Applications: WB, IHC
Reactivity: Human
Immunogen: Synthesized peptide derived from internal of human Cytochrome P450 8B1.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1.0mg / ml
Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20?C
Function: Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha-hydroxylated C27 steroids.
Tissue Specificity: Liver.
Sequence Similarities: Belongs to the cytochrome P450 family.
Cellular Location: Endoplasmic reticulum membrane. Microsome membrane.
Database Links:
  • Entrez Gene: 1582?Human
  • Omim: 602172?Human
  • SwissProt: Q9UNU6?Human
  • Unigene: 447793?Human
  • Unigene: 722743?Human
  • Synonyms:
  • 7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase Antibody
  • 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase Antibody
  • CP8B Antibody
  • CP8B1_HUMAN Antibody
  • CYP12 Antibody
  • CYP8B1 Antibody
  • CYPVIIIB1 Antibody
  • Cytochrome P450 8B1 Antibody
  • Cytochrome P450 subfamily VIIIB (sterol 12 alpha hydroxylase) polypeptide 1 Antibody
  • Cytochrome P450, family 8, subfamily B, polypeptide 1 Antibody
  • Sterol 12-alpha-hydroxylase Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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