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Anti-Cytochrome P450 2C8 Antibody

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产品名称: Anti-Cytochrome P450 2C8 Antibody
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Anti-Cytochrome P450 2C8 Antibody


Anti-Cytochrome P450 2C8 Antibody  的详细介绍
Name: Anti-Cytochrome P450 2C8 Antibody
See all Cytochrome P450 2C8 primary antibodies
Description: Rabbit polyclonal antibody to Cytochrome P450 2C8
Specificity: The antibody detects endogenous levels of total Cytochrome P450 2C8 protein.
Applications: WB, IHC
Reactivity: Human
Immunogen: Synthesized peptide derived from internal of human Cytochrome P450 2C8.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1.0mg / ml
Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20?C
Function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15- and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme responsible for the metabolism the anti-cancer drug paclitaxel (taxol).
Sequence Similarities: Belongs to the cytochrome P450 family.
Cellular Location: Endoplasmic reticulum membrane. Microsome membrane.
Database Links:
  • Entrez Gene: 1558?Human
  • Omim: 601129?Human
  • SwissProt: P10632?Human
  • Unigene: 709188?Human
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    Synonyms:
  • CP2C8_HUMAN Antibody
  • CPC8 Antibody
  • CYP2C8 Antibody
  • CYPIIC8 Antibody
  • Cytochrome P450 2C8 Antibody
  • Cytochrome P450 family 2 subfamily C polypeptide 8 Antibody
  • Cytochrome P450 form 1 Antibody
  • Cytochrome P450 IIC2 Antibody
  • Cytochrome P450 MP-12 Antibody
  • Cytochrome P450 MP-20 Antibody
  • Cytochrome P450 subfamily IIC (mephenytoin 4 hydroxylase) polypeptide 8 Antibody
  • Flavoprotein linked monooxygenase Antibody
  • Microsomal monooxygenase Antibody
  • MP 12/MP 20 Antibody
  • P450 form 1 Antibody
  • P450 IIC2 Antibody
  • P450 MP 12/MP 20 Antibody
  • S mephenytoin 4 hydroxylase Antibody
  • S-mephenytoin 4-hydroxylase Antibody
  • Xenobiotic monooxygenase Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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