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Anti-CYP46A1 Antibody

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产品名称: Anti-CYP46A1 Antibody
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Anti-CYP46A1 Antibody


Anti-CYP46A1 Antibody  的详细介绍
Name: Anti-CYP46A1 Antibody
See all CYP46A1 primary antibodies
Description: Rabbit polyclonal antibody to CYP46A1
Specificity: The antibody detects endogenous levels of total CYP46A1 protein.
Applications: WB, IHC
Reactivity: Human
Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human cytochrome P450, family 46, subfamily A, polypeptide 1
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1.1mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Involved in the turnover of cholesterol. It converts cholesterol into 24S-hydroxycholesterol and, to a lesser extent, 25-hydroxycholesterol. Has also activity with xenobiotic compounds, such as clotrimazole.
Tissue Specificity: Expressed in brain. The mRNA was broadly distributed with higher levels in gray matter zones and lower levels in regions rich in white matter. Not detected in fetal sample but its expression increases linearly with age.
Sequence Similarities: Belongs to the cytochrome P450 family.
Cellular Location: Endoplasmic reticulum membrane. Microsome membrane.
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