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Anti-CYP46A1 Antibody

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产品名称: Anti-CYP46A1 Antibody
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Anti-CYP46A1 Antibody


Anti-CYP46A1 Antibody  的详细介绍
Name: Anti-CYP46A1 Antibody
See all CYP46A1 primary antibodies
Description: Rabbit polyclonal antibody to CYP46A1.
Applications: WB, IHC
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:100.
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human CYP46A1.
Protein Length: 500
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Involved in the turnover of cholesterol. It converts cholesterol into 24S-hydroxycholesterol and, to a lesser extent, 25-hydroxycholesterol. Has also activity with xenobiotic compounds, such as clotrimazole.
Tissue Specificity: Expressed in brain. The mRNA was broadly distributed with higher levels in gray matter zones and lower levels in regions rich in white matter. Not detected in fetal sample but its expression increases linearly with age.
Sequence Similarities: Belongs to the cytochrome P450 family.
Cellular Location: Endoplasmic reticulum membrane. Microsome membrane.
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