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Anti-CYFIP2 Antibody

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产品名称: Anti-CYFIP2 Antibody
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Anti-CYFIP2 Antibody


Anti-CYFIP2 Antibody  的详细介绍
Name: Anti-CYFIP2 Antibody
See all CYFIP2 primary antibodies
Description: Rabbit polyclonal antibody to CYFIP2
Specificity: The antibody detects endogenous levels of total CYFIP2 protein.
Applications: WB, IHC
Reactivity: Human, Mouse
Immunogen: Fusion protein corresponding to residues near the C terminal of human cytoplasmic FMR1 interacting protein 2
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1.2mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Involved in T-cell adhesion and p53/TP53-dependent induction of apoptosis. Does not bind RNA.
Tissue Specificity: Expressed in T-cells. Increased expression is observed in CD4(+) T-lymphocytes from patients with multiple sclerosis (at protein level).
Sequence Similarities: Belongs to the CYFIP family.
Cellular Location: Cytoplasm. Nucleus. Cytoplasm > Perinuclear region. Cell junction > Synapse > Synaptosome.

Highly expressed in the perinuclear regionand enriched in synaptosomes (By similarity). Treatment with leptomycin-B triggers translocation to the nucleus (PubMed:17245118).
Database Links:
  • Entrez Gene: 26999?Human
  • Entrez Gene: 76884?Mouse
  • Omim: 606323?Human
  • SwissProt: Q96F07?Human
  • SwissProt: Q5SQX6?Mouse
  • Unigene: 910449?Human
  • Unigene: 293961?Mouse
    		•
    Synonyms:
  • CYFIP2 Antibody
  • CYFP2 Antibody
  • cytoplasmic FMR1 interacting protein 2 Antibody
  • KIAA1168 Antibody
  • p53 inducible protein Antibody
  • p53-inducible protein 121 Antibody
  • PIR121 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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