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Anti-CYBA Antibody

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Anti-CYBA Antibody


Anti-CYBA Antibody  的详细介绍
Name: Anti-CYBA Antibody
See all CYBA primary antibodies
Description: Rabbit polyclonal antibody to CYBA
Specificity: The antibody detects endogenous levels of total CYBA protein.
Applications: IHC
Reactivity: Human
Immunogen: Fusion protein corresponding to residues near the C terminal of human cytochrome b-245, alpha polypeptide
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1.6mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
Involvement in Disease: Granulomatous disease, chronic, cytochrome-b-negative, autosomal recessive: A disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections.
Sequence Similarities: Belongs to the p22phox family.
Post-Translational Modification: The heme prosthetic group could be coordinated with residues of the light chain, the heavy chain, or both, and it is possible that more than one heme is present per cytochrome b-245.
Cellular Location: Cell membrane.
Database Links:
  • Entrez Gene: 1535?Human
  • Omim: 608508?Human
  • SwissProt: P13498?Human
  • Unigene: 513803?Human
    		•
    Synonyms:
  • CYBA Antibody
  • Cytochrome b 245 alpha polypeptide Antibody
  • Cytochrome b 245 light chain Antibody
  • Cytochrome b alpha polypeptide Antibody
  • Cytochrome b(558) alpha chain Antibody
  • Cytochrome b(558) alpha subunit Antibody
  • Cytochrome b245 Light Chain/P22phox Antibody
  • Cytochrome b558 subunit alpha Antibody
  • Flavocytochrome b 558 alpha polypeptide Antibody
  • Neutrophil cytochrome b 22 kDa polypeptide Antibody
  • p22 phagocyte B-cytochrome Antibody
  • p22-phox Antibody
  • p22phox Antibody
  • Superoxide-generating NADPH oxidase light chain subunit Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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