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Anti-CXCR3 Antibody

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产品名称: Anti-CXCR3 Antibody
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简单介绍

Anti-CXCR3 Antibody


Anti-CXCR3 Antibody  的详细介绍
Name: Anti-CXCR3 Antibody
See all CXCR3 primary antibodies
Description: Rabbit polyclonal antibody to CXCR3
Specificity: The antibody detects endogenous levels of total CXCR3 protein.
Applications: WB, IHC
Reactivity: Human, Mouse
Immunogen: Fusion protein corresponding to residues near the N terminal of human chemokine (C-X-C motif) receptor 3
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 0.5mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Isoform 1: Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G-protein signaling pathway (PubMed:12782716). Binds to CCL21. Probably promotes cell chemotaxis response.
Tissue Specificity: Isoform 1 and isoform 2 are mainly expressed in heart, kidney, liver and skeletal muscle. Isoform 1 is also expressed in placenta. Isoform 2 is expressed in endothelial cells. Expressed in T-cells (at protein level).
Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.
Post-Translational Modification: Sulfation on Tyr-27 and Tyr-29 is essential for CXCL10 binding and subsequent signal transduction induction.
Cellular Location: Cell membrane.
Database Links:
  • Entrez Gene: 2833?Human
  • Entrez Gene: 12766?Mouse
  • Omim: 300574?Human
  • SwissProt: P49682?Human
  • SwissProt: O88410?Mouse
  • Unigene: 198252?Human
  • Unigene: 12876?Mouse
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    Synonyms:
  • C-X-C chemokine receptor type 3 Antibody
  • CD 183 Antibody
  • CD182 Antibody
  • CD183 Antibody
  • Chemokine (C X C motif) receptor 3 Antibody
  • Chemokine (C X C) receptor 3 Antibody
  • Chemokine CXC Motif Receptor 3 Antibody
  • CKR L2 Antibody
  • CKR-L2 Antibody
  • CKRL2 Antibody
  • CMKAR3 Antibody
  • CXC-R3 Antibody
  • CXCR-3 Antibody
  • CXCR3 Antibody
  • CXCR3_HUMAN Antibody
  • G Protein Coupled Receptor 9 Antibody
  • G protein-coupled receptor 9 Antibody
  • GPR9 Antibody
  • Interferon-inducible protein 10 receptor Antibody
  • IP-10 receptor Antibody
  • IP10 Antibody
  • IP10 R Antibody
  • IP10 receptor Antibody
  • IP10-R Antibody
  • IP10R Antibody
  • Mig R Antibody
  • Mig receptor Antibody
  • Mig-R Antibody
  • MIGR Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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