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Anti-CTSE Antibody

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产品名称: Anti-CTSE Antibody
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简单介绍

Anti-CTSE Antibody


Anti-CTSE Antibody  的详细介绍
Name: Anti-CTSE Antibody
See all CTSE primary antibodies
Description: Rabbit polyclonal antibody to CTSE
Specificity: The antibody detects endogenous levels of total CTSE protein.
Applications: WB, IHC
Reactivity: Human, Mouse
Immunogen: Fusion protein corresponding to a region derived from internal residues of human Cathepsin E
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 0.28mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.
Tissue Specificity: Expressed abundantly in the stomach, the Clara cells of the lung and activated B-lymphocytes, and at lower levels in lymph nodes, skin and spleen. Not expressed in resting B-lymphocytes.
Sequence Similarities: Belongs to the peptidase A1 family.
Post-Translational Modification: Glycosylated. The nature of the carbohydrate chain varies between cell types. In fibroblasts, the proenzyme contains a high mannose-type oligosaccharide, while the mature enzyme contains a complex-type oligosaccharide. In erythrocyte membranes, both the proenzyme and mature enzyme contain a complex-type oligosaccharide.
Cellular Location: Endosome.

The proenzyme is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome.
Database Links:
  • Entrez Gene: 1510?Human
  • Entrez Gene: 13034?Mouse
  • Omim: 116890?Human
  • SwissProt: P14091?Human
  • SwissProt: P70269?Mouse
  • Unigene: 644082?Human
    		•
    Synonyms:
  • CATE Antibody
  • CATE_HUMAN Antibody
  • Cathepsin E Antibody
  • Cathepsin E form II Antibody
  • CTSE Antibody
  • Erythrocyte membrane aspartic proteinase Antibody
  • Slow moving proteinase Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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