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Anti-CTPS (K109) Antibody

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产品名称: Anti-CTPS (K109) Antibody
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简单介绍

Anti-CTPS (K109) Antibody


Anti-CTPS (K109) Antibody  的详细介绍
Name: Anti-CTPS (K109) Antibody
See all CTPS primary antibodies
Description: Rabbit polyclonal antibody to CTPS (K109)
Specificity: CTPS (K109) pAb detects endogenous levels of CTPS protein.
Applications: WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 80-130 of Human CTPS.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 67 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Function: This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of activated lymphocytes and therefore in immunity.
Tissue Specificity: Widely expressed.
Involvement in Disease: Immunodeficiency 24: A life-threatening immunodeficiency, characterized by an impaired capacity of activated T and B cells to proliferate in response to antigen receptor-mediated activation. Patients have early onset of severe chronic viral infections, mostly caused by herpes viruses, including EBV and varicella zooster virus (VZV), and also suffer from recurrent encapsulated bacterial infections, a spectrum of infections typical of a combined deficiency of adaptive immunity.
Sequence Similarities: Belongs to the CTP synthase family.
Database Links:
  • Entrez Gene: 1503?Human
  • Entrez Gene: 51797?Mouse
  • Entrez Gene: 313560?Rat
  • Omim: 123860?Human
  • SwissProt: P17812?Human
  • SwissProt: P70698?Mouse
  • Unigene: 473087?Human
  • Unigene: 1815?Mouse
  • Unigene: 162834?Rat
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    Synonyms:
  • CTP synthase Antibody
  • CTP synthase 1 Antibody
  • CTP synthetase Antibody
  • CTP synthetase 1 Antibody
  • CTPS Antibody
  • Cytidine 5 prime triphosphate synthetase Antibody
  • Cytidine 5' triphosphate synthetase Antibody
  • IMD24 Antibody
  • UTP ammonia ligase 1 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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