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Anti-CTDSP1 Antibody

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产品名称: Anti-CTDSP1 Antibody
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简单介绍

Anti-CTDSP1 Antibody


Anti-CTDSP1 Antibody  的详细介绍
Name: Anti-CTDSP1 Antibody
See all CTDSP1 primary antibodies
Description: Rabbit polyclonal antibody to CTDSP1
Specificity: The antibody detects endogenous levels of total CTDSP1 protein.
Applications: WB, IHC
Reactivity: Human
Immunogen: Synthesized peptide derived from N-terminal of human CTDSP1.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1.0mg / ml
Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20?C
Function: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
Tissue Specificity: Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta.
Cellular Location: Nucleus.

Colocalizes with RNA polymerase II.
Database Links:
  • Entrez Gene: 58190?Human
  • Omim: 605323?Human
  • SwissProt: Q9GZU7?Human
  • Unigene: 444468?Human
    		•
    Synonyms:
  • Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 1 Antibody
  • Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 Antibody
  • CTD (carboxy terminal domain RNA polymerase II polypeptide A) small phosphatase 1 Antibody
  • CTD small phosphatase 1 Antibody
  • CTDS1_HUMAN Antibody
  • CTDSP1 Antibody
  • NIF3 Antibody
  • NLI IF Antibody
  • NLI interacting factor 3 Antibody
  • NLI-IF Antibody
  • NLI-interacting factor 3 Antibody
  • NLIIF Antibody
  • Nuclear LIM interactor interacting factor 3 Antibody
  • Nuclear LIM interactor-interacting factor 3 Antibody
  • SCP1 Antibody
  • Small C-terminal domain phosphatase 1 Antibody
  • Small CTD phosphatase 1 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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