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Anti-CSTB Antibody

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产品名称: Anti-CSTB Antibody
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简单介绍

Anti-CSTB Antibody


Anti-CSTB Antibody  的详细介绍
Name: Anti-CSTB Antibody
See all CSTB primary antibodies
Description: Rabbit polyclonal antibody to CSTB
Specificity: The antibody detects endogenous levels of total CSTB protein.
Applications: WB, IHC
Reactivity: Human, Mouse
Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human cystatin B (stefin B)
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 2.2mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: This is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B.
Involvement in Disease: Epilepsy, progressive myoclonic 1: An autosomal recessive disorder characterized by severe, stimulus-sensitive myoclonus and tonic-clonic seizures. The onset, occurring between 6 and 13 years of age, is characterized by convulsions. Myoclonus begins 1 to 5 years later. The twitchings occur predominantly in the proximal muscles of the extremities and are bilaterally symmetrical, although asynchronous. At first small, they become late in the clinical course so violent that the victim is thrown to the floor. Mental deterioration and eventually dementia develop.
Sequence Similarities: Belongs to the cystatin family.
Cellular Location: Cytoplasm. Nucleus.
Database Links:
  • Entrez Gene: 1476?Human
  • Entrez Gene: 13014?Mouse
  • Omim: 601145?Human
  • SwissProt: P04080?Human
  • SwissProt: Q62426?Mouse
  • Unigene: 695?Human
  • Unigene: 6095?Mouse
    		•
    Synonyms:
  • CHROW21 Antibody
  • CPI B Antibody
  • CPI-B Antibody
  • CST 6 Antibody
  • CST6 Antibody
  • CSTB Antibody
  • Cystatin B Antibody
  • Cystatin B (stefin B) Antibody
  • Cystatin-B Antibody
  • CYTB Antibody
  • CYTB_HUMAN Antibody
  • EPM1 Antibody
  • EPM1A Antibody
  • Liver thiol proteinase inhibitor Antibody
  • PME Antibody
  • Stefin B Antibody
  • Stefin-B Antibody
  • STF B Antibody
  • STFB Antibody
  • ULD Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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