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Anti-CSNK1E Antibody

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产品名称: Anti-CSNK1E Antibody
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简单介绍

Anti-CSNK1E Antibody


Anti-CSNK1E Antibody  的详细介绍
Name: Anti-CSNK1E Antibody
See all CSNK1E primary antibodies
Description: Rabbit polyclonal antibody to CSNK1E
Specificity: The antibody detects endogenous levels of total CSNK1E protein.
Applications: WB, IHC
Reactivity: Human
Immunogen: Fusion protein corresponding to residues near the C terminal of human casein kinase 1, epsilon
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 3.1mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation.
Tissue Specificity: Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle. Expressed in monocytes and lymphocytes but not in granulocytes.
Sequence Similarities: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
Post-Translational Modification: Autophosphorylated. Partially dephosphorylated by PPP5C. May be dephosphorylated by PP1.
Cellular Location: Cytoplasm. Nucleus.
Database Links:
  • Entrez Gene: 1454?Human
  • Omim: 600863?Human
  • SwissProt: P49674?Human
  • Unigene: 474833?Human
    		•
    Synonyms:
  • Casein kinase 1 epsilon Antibody
  • Casein kinase I Antibody
  • Casein kinase I epsilon Antibody
  • Casein kinase I isoform epsilon Antibody
  • CK1 epsilon Antibody
  • CKI epsilon Antibody
  • CKI-epsilon Antibody
  • CKIe Antibody
  • CKIepsilon Antibody
  • CSNK 1E Antibody
  • CSNK1E Antibody
  • DBT Antibody
  • Doubletime, Drosophila, homolog of Antibody
  • EC 2.7.11.1 Antibody
  • epsilon isoform Antibody
  • HCK IE Antibody
  • KC1E Antibody
  • KC1E_HUMAN Antibody
  • kinase CK1 epsilon Antibody
  • MGC 10398 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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