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Anti-CRMP-2 (Phospho-Thr509) Antibody

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产品名称: Anti-CRMP-2 (Phospho-Thr509) Antibody
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Anti-CRMP-2 (Phospho-Thr509) Antibody


Anti-CRMP-2 (Phospho-Thr509) Antibody  的详细介绍
Name: Anti-CRMP-2 (Phospho-Thr509) Antibody
See all CRMP-2 primary antibodies
Description: Rabbit polyclonal antibody to CRMP-2 (Phospho-Thr509)
Specificity: The antibody detects endogenous levels of CRMP-2 only when phosphorylated at threonine 509.
Applications: WB, IHC
Dilutions: Western blotting: 1:500~1:1000Immunohistochemistry: 1:50~1:100
Reactivity: Human
Immunogen: Peptide sequence around phosphorylation site of threonine 509 (S-V-T(p)-P-K) derived from Human CRMP-2.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Concentration: 1.0mg / ml
Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20?C / 1 year
Function: Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.
Tissue Specificity: Ubiquitous.
Sequence Similarities: Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
Post-Translational Modification: 3F4, a monoclonal antibody which strongly stains neurofibrillary tangles in Alzheimer disease brains, specifically labels DPYSL2 when phosphorylated on Ser-518, Ser-522 and Thr-509.
Cellular Location: Cytoplasm > Cytosol. Cytoplasm > Cytoskeleton. Membrane.

Tightly but non-covalently associated with membranes.
Database Links:
  • Entrez Gene: 1808?Human
  • Omim: 602463?Human
  • SwissProt: Q16555?Human
  • Unigene: 173381?Human
  • Unigene: 593187?Human
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    Synonyms:
  • Collapsin response mediator protein Antibody
  • Collapsin response mediator protein 2 Antibody
  • Collapsin response mediator protein hCRMP 2 Antibody
  • CRAM Antibody
  • CRMP 2 Antibody
  • CRMP-2 Antibody
  • CRMP2 Antibody
  • DHPRP 2 Antibody
  • DHPRP2 Antibody
  • Dihydropyrimidinase 2 Antibody
  • Dihydropyrimidinase like 2 Antibody
  • Dihydropyrimidinase like 2 long form Antibody
  • Dihydropyrimidinase related protein 2 Antibody
  • Dihydropyrimidinase-related protein 2 Antibody
  • DPYL 2 Antibody
  • DPYL2 Antibody
  • DPYL2_HUMAN Antibody
  • DPYSL 2 Antibody
  • Dpysl2 Antibody
  • DRP-2 Antibody
  • DRP2 Antibody
  • Musunc 33 Antibody
  • Musunc33 Antibody
  • N2A3 Antibody
  • TOAD 64 Antibody
  • TOAD64 Antibody
  • ULIP 2 protein Antibody
  • ULIP-2 Antibody
  • Ulip2 Antibody
  • Unc-33-like phosphoprotein 2 Antibody
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    Information: Target information shown above is from the UniProt Consortium.
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