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Anti-CRHR2 Antibody

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产品名称: Anti-CRHR2 Antibody
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简单介绍

Anti-CRHR2 Antibody


Anti-CRHR2 Antibody  的详细介绍
Name: Anti-CRHR2 Antibody
See all CRHR2 primary antibodies
Description: Rabbit polyclonal antibody to CRHR2
Specificity: The antibody detects endogenous levels of total CRHR2 protein.
Applications: WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human corticotropin releasing hormone receptor 2
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1.9mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.
Sequence Similarities: Belongs to the G-protein coupled receptor 2 family.
Post-Translational Modification: A N-glycosylation site within the signal peptide impedes its proper cleavage and function.
Cellular Location: Cell membrane.
Database Links:
  • Entrez Gene: 1395?Human
  • Entrez Gene: 12922?Mouse
  • Entrez Gene: 64680?Rat
  • Omim: 602034?Human
  • SwissProt: Q13324?Human
  • SwissProt: Q60748?Mouse
  • SwissProt: P47866?Rat
  • Unigene: 546246?Human
  • Unigene: 236081?Mouse
  • Unigene: 10023?Rat
    		•
    Synonyms:
  • Corticotropin Releasing Factor Receptor 2 Antibody
  • Corticotropin releasing hormone receptor 2 Antibody
  • Corticotropin-releasing factor receptor 2 Antibody
  • Corticotropin-releasing hormone receptor 2 Antibody
  • CRF 2 Antibody
  • CRF 2R Antibody
  • CRF R2 Antibody
  • CRF RB Antibody
  • CRF-R-2 Antibody
  • CRF-R2 Antibody
  • CRF2 Antibody
  • CRF2 receptor beta isoform Antibody
  • CRF2R Antibody
  • CRFR 2 Antibody
  • CRFR-2 Antibody
  • CRFR2 Antibody
  • CRFR2_HUMAN Antibody
  • CRH 2R Antibody
  • CRH R2 Antibody
  • CRH-R-2 Antibody
  • CRH-R2 Antibody
  • CRH2R Antibody
  • CRHR 2 Antibody
  • Crhr2 Antibody
  • HM CRF Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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