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Anti-CREM (I106) Antibody

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产品名称: Anti-CREM (I106) Antibody
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Anti-CREM (I106) Antibody


Anti-CREM (I106) Antibody  的详细介绍
Name: Anti-CREM (I106) Antibody
See all CREM primary antibodies
Description: Rabbit polyclonal antibody to CREM (I106)
Specificity: CREM (I106) pAb detects endogenous levels of CREM protein.
Applications: WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 80-130 of Human CREM.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 35 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Function: Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid maturation (PubMed:10373550).
Tissue Specificity: Expressed in testes (round spermatids) (at protein level). Isoform 14 is the major activator form in testes.
Sequence Similarities: Belongs to the bZIP family.
Post-Translational Modification: Isoform 9 is ubiquitinated by CDC34 and RAD6B in order to be degraded by the proteasome.
Cellular Location: Nucleus.
Database Links:
  • Entrez Gene: 1390?Human
  • Entrez Gene: 12916?Mouse
  • Entrez Gene: 25620?Rat
  • Omim: 123812?Human
  • SwissProt: Q03060?Human
  • SwissProt: P27699?Mouse
  • SwissProt: Q03061?Rat
  • Unigene: 200250?Human
  • Unigene: 5244?Mouse
  • Unigene: 10251?Rat
    		•
    Synonyms:
  • cAMP response element modulator Antibody
  • cAMP responsive element modulator Antibody
  • cAMP-responsive element modulator Antibody
  • CREM Antibody
  • CREM-2 Antibody
  • CREM_HUMAN Antibody
  • hCREM 2 Antibody
  • hCREM-2 Antibody
  • hCREM2 Antibody
  • ICER Antibody
  • Inducible cAMP early repressor Antibody
  • Inducible cAMP early repressor ICER Antibody
  • MGC111110 Antibody
  • MGC17881 Antibody
  • MGC41893 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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