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Anti-Collagen XVIII α1 Antibody

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产品名称: Anti-Collagen XVIII α1 Antibody
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Anti-Collagen XVIII α1 Antibody


Anti-Collagen XVIII α1 Antibody  的详细介绍
Name: Anti-Collagen XVIII α1 Antibody
See all Collagen XVIII α1 primary antibodies
Description: Rabbit polyclonal antibody to Collagen XVIII α1
Specificity: The antibody detects endogenous levels of total Collagen XVIII α1 protein.
Applications: IHC, IF
Reactivity: Human, Mouse
Immunogen: Synthesized peptide derived from internal of human Collagen XVIII α1.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1.0mg / ml
Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20?C
Function: COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube.
Tissue Specificity: Present in multiple organs with highest levels in liver, lung and kidney.
Involvement in Disease: Knobloch syndrome 1: A developmental disorder primarily characterized by typical eye abnormalities, including high myopia, cataracts, dislocated lens, vitreoretinal degeneration, and retinal detachment, with occipital skull defects, which can range from occipital encephalocele to occult cutis aplasia.
Sequence Similarities: Belongs to the multiplexin collagen family.
Post-Translational Modification: Prolines at the third position of the tripeptide repeating unit (G-X-Y) of the triple-helical regions are hydroxylated.
Cellular Location: Secreted > Extracellular space > Extracellular matrix.
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