产品资料

Anti-Collagen III Antibody

如果您对该产品感兴趣的话,可以
产品名称: Anti-Collagen III Antibody
产品型号:
产品展商: 其它品牌
产品文档: 无相关文档

简单介绍

Anti-Collagen III Antibody


Anti-Collagen III Antibody  的详细介绍
Name: Anti-Collagen III Antibody
See all Collagen III primary antibodies
Description: Rabbit polyclonal antibody to Collagen III
Specificity: The antibody detects endogenous levels of total collagen III protein.
Applications: IHC, IF
Reactivity: Human, Mouse
Immunogen: Synthesized peptide derived from internal of human collagen III.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1.0mg / ml
Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20?C
Function: Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12.
Involvement in Disease: Ehlers-Danlos syndrome 3: A connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity. It is a form of Ehlers-Danlos syndrome characterized by marked joint hyperextensibility without skeletal deformity.

Ehlers-Danlos syndrome 4: The most severe form of Ehlers-Danlos syndrome, a connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity. Characterized by the joint and dermal manifestations as in other forms of the syndrome, characteristic facial features (acrogeria) in most patients, and by proneness to spontaneous rupture of bowel and large arteries. The vascular complications may affect all anatomical areas.

Aortic aneurysm, familial abdominal: A common multifactorial disorder characterized by permanent dilation of the abdominal aorta, usually due to degenerative changes in the aortic wall. Histologically, AAA is characterized by signs of chronic inflammation, destructive remodeling of the extracellular matrix, and depletion of vascular smooth muscle cells.
Sequence Similarities: Belongs to the fibrillar collagen family.
Post-Translational Modification: Proline residues at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
Cellular Location: Secreted > Extracellular space > Extracellular matrix.
Database Links:
  • Entrez Gene: 1281?Human
  • Entrez Gene: 12825?Mouse
  • Omim: 120180?Human
  • SwissProt: P02461?Human
  • SwissProt: P08121?Mouse
  • Unigene: 443625?Human
  • Unigene: 249555?Mouse
    		•
    Synonyms:
  • Alpha 1 type III collagen Antibody
  • Alpha1 (III) collagen Antibody
  • CO3A1_HUMAN Antibody
  • COL 3A1 Antibody
  • COL3A1 Antibody
  • Collagen alpha 1(III) chain Antibody
  • Collagen alpha-1(III) chain Antibody
  • Collagen III Antibody
  • Collagen III alpha 1 chain precursor Antibody
  • Collagen III alpha 1 polypeptide Antibody
  • Collagen type III alpha Antibody
  • Collagen type III alpha 1 Antibody
  • Collagen type III alpha 1 (Ehlers Danlos syndrome type IV autosomal dominant) Antibody
  • Collagen type III alpha 1 chain Antibody
  • Collagen, fetal Antibody
  • EDS4A Antibody
  • Ehlers Danlos syndrome type IV, autosomal dominant Antibody
  • Fetal collagen Antibody
  • Type III collagen Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
    产品留言
    标题
    联系人
    联系电话
    内容
    验证码
    点击换一张
    注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
    2.如有必要,请您留下您的详细联系方式!

    沪公网安备 31011202007337号