产品资料

Anti-COL4A3BP Antibody

如果您对该产品感兴趣的话,可以
产品名称: Anti-COL4A3BP Antibody
产品型号:
产品展商: 其它品牌
产品文档: 无相关文档

简单介绍

Anti-COL4A3BP Antibody


Anti-COL4A3BP Antibody  的详细介绍
Name: Anti-COL4A3BP Antibody
See all COL4A3BP primary antibodies
Description: Goat polyclonal antibody to COL4A3BP.
Applications: ELISA, WB
Reactivity: Human
Immunogen: Synthetic peptide corresponding to Human COL4A3BP (internal region).
Sequence: C-KREDSWQKRLDKETEK
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 µg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.
Tissue Specificity: Widely expressed.
Involvement in Disease: Mental retardation, autosomal dominant 34: A form of mental retardation, a disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period.
Post-Translational Modification: Phosphorylation on Ser-132 decreases the affinity toward phosphatidylinositol 4-phosphate at Golgi membranes and reduces ceramide transfer activity. Inactivated by hyperphosphorylation of serine residues by CSNK1G2/CK1 that triggers dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis.
Cellular Location: Cytoplasm. Golgi apparatus. Endoplasmic reticulum.

Preferentially localized to the Golgi apparatus.
Database Links:
  • Entrez Gene: 10087 Human
  • Omim: 604677 Human
  • SwissProt: Q9Y5P4 Human
  • Unigene: 270437 Human
    		•
    Synonyms:
  • Alpha 3 type IV collagen binding protein Antibody
  • C43BP_HUMAN Antibody
  • Ceramide transfer protein Antibody
  • Ceramide transporter Antibody
  • CERT Antibody
  • Cert protein Antibody
  • CERTL Antibody
  • COL4A3BP Antibody
  • Collagen type IV alpha 3 (Goodpasture antigen) binding protein Antibody
  • Collagen type IV alpha 3 binding protein Antibody
  • Collagen type IV alpha-3-binding protein Antibody
  • FLJ20597 Antibody
  • Goodpasture antigen binding protein Antibody
  • Goodpasture antigen-binding protein Antibody
  • GPBP Antibody
  • hCERT Antibody
  • Lipid transfer protein CERTL Antibody
  • Procollagen type IV alpha 3 (Goodpasture antigen) binding protein Antibody
  • StAR related lipid transfer (START) domain containing 11 Antibody
  • StAR related lipid transfer protein 11 Antibody
  • StAR-related lipid transfer protein 11 Antibody
  • StARD 11 Antibody
  • StARD11 Antibody
  • START domain containing 11 Antibody
  • START domain containing protein 11 Antibody
  • START domain-containing protein 11 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
    产品留言
    标题
    联系人
    联系电话
    内容
    验证码
    点击换一张
    注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
    2.如有必要,请您留下您的详细联系方式!

    沪公网安备 31011202007337号