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Anti-COL4A3BP Antibody

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产品名称: Anti-COL4A3BP Antibody
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简单介绍

Anti-COL4A3BP Antibody


Anti-COL4A3BP Antibody  的详细介绍
Name: Anti-COL4A3BP Antibody
See all COL4A3BP primary antibodies
Description: Rabbit polyclonal antibody to COL4A3BP
Specificity: The antibody detects endogenous levels of total COL4A3BP protein.
Applications: WB, IHC
Reactivity: Human, Mouse
Immunogen: Fusion protein corresponding to a region derived from internal residues of human collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 2.6mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.
Tissue Specificity: Widely expressed.
Involvement in Disease: Mental retardation, autosomal dominant 34: A form of mental retardation, a disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period.
Post-Translational Modification: Phosphorylation on Ser-132 decreases the affinity toward phosphatidylinositol 4-phosphate at Golgi membranes and reduces ceramide transfer activity. Inactivated by hyperphosphorylation of serine residues by CSNK1G2/CK1 that triggers dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis.
Cellular Location: Cytoplasm. Golgi apparatus. Endoplasmic reticulum.

Preferentially localized to the Golgi apparatus.
Database Links:
  • Entrez Gene: 10087?Human
  • Entrez Gene: 68018?Mouse
  • Omim: 604677?Human
  • SwissProt: Q9Y5P4?Human
  • SwissProt: Q9EQG9?Mouse
  • Unigene: 270437?Human
  • Unigene: 24125?Mouse
    		•
    Synonyms:
  • Alpha 3 type IV collagen binding protein Antibody
  • C43BP_HUMAN Antibody
  • Ceramide transfer protein Antibody
  • Ceramide transporter Antibody
  • CERT Antibody
  • Cert protein Antibody
  • CERTL Antibody
  • COL4A3BP Antibody
  • Collagen type IV alpha 3 (Goodpasture antigen) binding protein Antibody
  • Collagen type IV alpha 3 binding protein Antibody
  • Collagen type IV alpha-3-binding protein Antibody
  • FLJ20597 Antibody
  • Goodpasture antigen binding protein Antibody
  • Goodpasture antigen-binding protein Antibody
  • GPBP Antibody
  • hCERT Antibody
  • Lipid transfer protein CERTL Antibody
  • Procollagen type IV alpha 3 (Goodpasture antigen) binding protein Antibody
  • StAR related lipid transfer (START) domain containing 11 Antibody
  • StAR related lipid transfer protein 11 Antibody
  • StAR-related lipid transfer protein 11 Antibody
  • StARD 11 Antibody
  • StARD11 Antibody
  • START domain containing 11 Antibody
  • START domain containing protein 11 Antibody
  • START domain-containing protein 11 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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