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Anti-CNOT8 Antibody

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产品名称: Anti-CNOT8 Antibody
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简单介绍

Anti-CNOT8 Antibody


Anti-CNOT8 Antibody  的详细介绍
Name: Anti-CNOT8 Antibody
See all CNOT8 primary antibodies
Description: Rabbit polyclonal antibody to CNOT8
Specificity: The antibody detects endogenous level of total CNOT8 polyclonal antibody.
Applications: IHC
Reactivity: Human
Immunogen: Recombinant human CCR4-NOT transcription complex subunit 8 protein (1-292aa)
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen Affinity Purified
Concentration: 1.0mg / mL
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20?C
Function: Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.
Sequence Similarities: Belongs to the CAF1 family.
Cellular Location: Cytoplasm. Nucleus.
Database Links:
  • Entrez Gene: 9337?Human
  • Omim: 603731?Human
  • SwissProt: Q9UFF9?Human
  • Unigene: 26703?Human
    		•
    Synonyms:
  • CAF 1 Antibody
  • CAF 2 Antibody
  • CAF1 Antibody
  • CAF1 like protein Antibody
  • CAF1-like protein Antibody
  • CAF2 Antibody
  • CALIF Antibody
  • CALIFp Antibody
  • CCR4 associated factor 8 Antibody
  • CCR4 NOT transcription complex subunit 8 Antibody
  • CCR4-associated factor 8 Antibody
  • CCR4-NOT transcription complex subunit 8 Antibody
  • CNOT 8 Antibody
  • CNOT8 Antibody
  • CNOT8_HUMAN Antibody
  • hCAF1 Antibody
  • PGK promoter directed over production Antibody
  • POP 2 Antibody
  • POP2 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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