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Anti-CLK1 Antibody

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简单介绍

Anti-CLK1 Antibody


Anti-CLK1 Antibody  的详细介绍
Name: Anti-CLK1 Antibody
See all CLK1 primary antibodies
Description: Rabbit polyclonal antibody to CLK1
Specificity: The antibody detects endogenous levels of total CLK1 protein.
Applications: WB, IF
Reactivity: Human, Mouse
Immunogen: Synthesized peptide derived from internal of human CLK1.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1.0mg / ml
Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20˚C
Function: Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA.
Tissue Specificity: Endothelial cells.
Sequence Similarities: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily.
Post-Translational Modification: Autophosphorylates on all three types of residues.
Cellular Location: Nucleus.
Database Links:
  • Entrez Gene: 1195 Human
  • Entrez Gene: 12747 Mouse
  • Omim: 601951 Human
  • SwissProt: P49759 Human
  • SwissProt: P22518 Mouse
  • Unigene: 433732 Human
  • Unigene: 1761 Mouse
  • Synonyms:
  • CDC like kinase 1 Antibody
  • CDC-like kinase 1 Antibody
  • CDC28/CDC2 like kinase Antibody
  • CLK Antibody
  • CLK/STY Antibody
  • CLK1 Antibody
  • CLK1_HUMAN Antibody
  • Dual specificity protein kinase CLK1 Antibody
  • Protein tyrosine kinase STY Antibody
  • STY Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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