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Anti-Cleaved-Caspase-2 p18 (G170) Antibody

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产品名称: Anti-Cleaved-Caspase-2 p18 (G170) Antibody
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Anti-Cleaved-Caspase-2 p18 (G170) Antibody


Anti-Cleaved-Caspase-2 p18 (G170) Antibody  的详细介绍
Name: Anti-Cleaved-Caspase-2 p18 (G170) Antibody
See all Cleaved-Caspase-2 p18 primary antibodies
Description: Rabbit polyclonal antibody to Cleaved-Caspase-2 p18 (G170)
Specificity: Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-2 p18 protein resulting from cleavage adjacent to G170.
Applications: WB, ELISA
Reactivity: Human
Immunogen: Synthesized peptide derived from the Internal region of human Caspase-2 p18.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1mg / ml
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage: Store at -20˚C / 1 year
Function: Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.
Tissue Specificity: Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In *****s, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.
Sequence Similarities: Belongs to the peptidase C14A family.
Post-Translational Modification: The mature protease can process its own propeptide, but not that of other caspases.
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