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Anti-CLCN4 Antibody

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产品名称: Anti-CLCN4 Antibody
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简单介绍

Anti-CLCN4 Antibody


Anti-CLCN4 Antibody  的详细介绍
Name: Anti-CLCN4 Antibody
See all CLCN4 primary antibodies
Description: Rabbit polyclonal antibody to CLCN4
Specificity: The antibody detects endogenous levels of total CLCN4 protein.
Applications: WB, IHC, IF
Reactivity: Human, Mouse, Rat
Immunogen: Synthesized peptide derived from internal of human CLCN4.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1.0mg / ml
Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20?C
Function: Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons.
Tissue Specificity: Abundant in skeletal muscle and also detectable in brain and heart.
Involvement in Disease: Mental retardation, X-linked 49: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Intellectual deficiency is the only primary symptom of non-syndromic X-linked mental retardation, while syndromic mental retardation presents with associated physical, neurological and/or psychiatric manifestations.
Sequence Similarities: Belongs to the chloride channel (TC 2.A.49) family. ClC-4/CLCN4 subfamily.
Cellular Location: Early endosome membrane. Late endosome membrane. Endoplasmic reticulum membrane.
Database Links:
  • Entrez Gene: 1183?Human
  • Entrez Gene: 12727?Mouse
  • Entrez Gene: 60586?Rat
  • Omim: 302910?Human
  • SwissProt: P51793?Human
  • SwissProt: Q61418?Mouse
  • SwissProt: P51794?Rat
  • Unigene: 495674?Human
  • Unigene: 297883?Mouse
  • Unigene: 488576?Mouse
  • Unigene: 44406?Rat
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    Synonyms:
  • Chloride channel 4 Antibody
  • Chloride channel protein 4 Antibody
  • Chloride channel, voltage sensitive 4 Antibody
  • Chloride transporter ClC-4 Antibody
  • ClC 4A Antibody
  • ClC-4 Antibody
  • CLC4 Antibody
  • ClC4A Antibody
  • CLCN4 Antibody
  • CLCN4_HUMAN Antibody
  • H(+)/Cl(-) exchange transporter 4 Antibody
  • MGC163150 Antibody
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    Information: Target information shown above is from the UniProt Consortium.
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