产品资料

Anti-Claudin-7 (S204) Antibody

如果您对该产品感兴趣的话,可以
产品名称: Anti-Claudin-7 (S204) Antibody
产品型号:
产品展商: 其它品牌
产品文档: 无相关文档

简单介绍

Anti-Claudin-7 (S204) Antibody


Anti-Claudin-7 (S204) Antibody  的详细介绍
Name: Anti-Claudin-7 (S204) Antibody
See all Claudin-7 primary antibodies
Description: Rabbit polyclonal antibody to Claudin-7 (S204)
Specificity: Claudin-7 (S204) pAb detects endogenous levels of Claudin-7 protein.
Applications: WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 171-220 of Human Claudin-7.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 23,32kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Function: Plays a major role in tight junction-specific obliteration of the intercellular space.
Tissue Specificity: Expressed in kidney, lung and prostate. Isoform 1 seems to be predominant, except in some normal prostate samples, where isoform 2 is the major form. Down-regulated in breast cancers, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS) and invasive ductal carcinoma (IDC) (at protein level), as well as in several cancer cell lines. Loss of expression correlates with histological grade, occurring predominantly in high-grade lesions.
Sequence Similarities: Belongs to the claudin family.
Post-Translational Modification: Phosphorylated.
Cellular Location: Cell membrane. Lateral cell membrane. Cell junction > Tight junction.

Co-localizes with EPCAM at the lateral cell membrane and tight junction.
Database Links:
  • Entrez Gene: 1366?Human
  • Entrez Gene: 53624?Mouse
  • Entrez Gene: 65132?Rat
  • Omim: 609131?Human
  • SwissProt: O95471?Human
  • SwissProt: Q9Z261?Mouse
  • SwissProt: Q9Z1L1?Rat
  • Unigene: 513915?Human
  • Unigene: 281896?Mouse
  • Unigene: 32259?Rat
    		•
    Synonyms:
  • CEPTR L2 Antibody
  • CEPTRL 2 Antibody
  • CEPTRL2 Antibody
  • Claudin 1 Antibody
  • Claudin 7 Antibody
  • Claudin 9 Antibody
  • Claudin-7 Antibody
  • Claudin1 Antibody
  • Claudin7 Antibody
  • Claudin9 Antibody
  • CLD7_HUMAN Antibody
  • CLDN 7 Antibody
  • CLDN-7 Antibody
  • CLDN7 Antibody
  • Clostridium perfringens enterotoxin receptor like 2 Antibody
  • CPETR L2 Antibody
  • CPETRL 2 Antibody
  • CPETRL2 Antibody
  • Hs.84359 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
    产品留言
    标题
    联系人
    联系电话
    内容
    验证码
    点击换一张
    注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
    2.如有必要,请您留下您的详细联系方式!

    沪公网安备 31011202007337号