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Anti-CKAP2 Antibody

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产品名称: Anti-CKAP2 Antibody
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简单介绍

Anti-CKAP2 Antibody


Anti-CKAP2 Antibody  的详细介绍
Name: Anti-CKAP2 Antibody
See all CKAP2 primary antibodies
Description: Rabbit polyclonal antibody to CKAP2
Specificity: The antibody detects endogenous levels of total CKAP2 protein.
Applications: IHC
Reactivity: Human
Immunogen: Full length fusion protein
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 2.9mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53-dependent manner (By similarity).
Tissue Specificity: Abundant in testis, thymus, and in tumor derived cell lines, while barely detectable in liver, prostate, and kidney.
Sequence Similarities: Belongs to the CKAP2 family.
Cellular Location: Cytoplasm > Cytoskeleton. Cytoplasm > Cytoskeleton > Spindle. Cytoplasm > Cytoskeleton > Spindle pole.

Contrary to the ectopically expressed protein, endogenous CKAP2 does not colocalize with microtubules in G1, S and early G2. At late G2 and prophase after separation of duplicated centrosomes, colocalizes with gamma-tubulin and centrosome-proximal microtubules. From prometaphase through anaphase B, colocalizes with mitotic spindle poles and spindle microtubules. During cytokinesis, absent from midbody microtubules.
Database Links:
  • Entrez Gene: 26586?Human
  • Omim: 611569?Human
  • SwissProt: Q8WWK9?Human
  • Unigene: 444028?Human
  • Unigene: 521482?Human
  • Unigene: 728722?Human
    		•
    Synonyms:
  • AI461656 Antibody
  • AW228814 Antibody
  • CKAP 2 Antibody
  • CKAP2 Antibody
  • CKAP2_HUMAN Antibody
  • CTCL tumor antigen se20 10 Antibody
  • CTCL tumor antigen se20-10 Antibody
  • Cytoskeleton associated protein 2 Antibody
  • Cytoskeleton-associated protein 2 Antibody
  • DKFZp686L1238 Antibody
  • FLJ10749 Antibody
  • LB1 Antibody
  • se20 10 Antibody
  • TMAP Antibody
  • Tumor and microtubule associated protein Antibody
  • Tumor associated microtubule associated protein Antibody
  • Tumor- and microtubule-associated protein Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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