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Anti-CHRNA4 Antibody

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产品名称: Anti-CHRNA4 Antibody
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简单介绍

Anti-CHRNA4 Antibody


Anti-CHRNA4 Antibody  的详细介绍
Name: Anti-CHRNA4 Antibody
See all CHRNA4 primary antibodies
Description: Rabbit polyclonal antibody to CHRNA4
Specificity: The antibody detects endogenous levels of total CHRNA4 protein.
Applications: WB, IHC
Reactivity: Human
Immunogen: Fusion protein corresponding to a region derived from internal residues of human cholinergic receptor, nicotinic, alpha 4 (neuronal)
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1.2mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions.
Involvement in Disease: Epilepsy, nocturnal frontal lobe, 1: An autosomal dominant focal epilepsy characterized by nocturnal seizures with hyperkinetic automatisms and poorly organized stereotyped movements.
Sequence Similarities: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-4/CHRNA4 sub-subfamily.
Cellular Location: Cell junction > Synapse > Postsynaptic cell membrane. Cell membrane. Cell membrane.
Database Links:
  • Entrez Gene: 1137?Human
  • Omim: 118504?Human
  • SwissProt: P43681?Human
  • Unigene: 10734?Human
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    Synonyms:
  • A4 nicotinic receptor Antibody
  • Acetylcholine receptor alpha 4 neural Antibody
  • Acetylcholine receptor neuronal nicotinic alpha 4 subunit Antibody
  • ACH 4 Antibody
  • ACH4 Antibody
  • ACHA4_HUMAN Antibody
  • AChR Antibody
  • Acra 4 Antibody
  • Acra4 Antibody
  • Alpha4 nAChR Antibody
  • BFNC Antibody
  • Cholinergic receptor nicotinic alpha 4 Antibody
  • Cholinergic receptor nicotinic alpha polypeptide 4 Antibody
  • CHRNA 4 Antibody
  • CHRNA4 Antibody
  • EBN Antibody
  • EBN 1 Antibody
  • EBN1 Antibody
  • NACHR Antibody
  • NACRA 4 Antibody
  • NACRA4 Antibody
  • Neuronal acetylcholine receptor subunit alpha-4 Antibody
  • Neuronal nicotinic acetylcholine receptor alpha 4 subunit Antibody
  • Nicotinic Acetylcholine Receptor alpha 4 Antibody
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    Information: Target information shown above is from the UniProt Consortium.
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