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Anti-CHRNA2 Antibody

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产品名称: Anti-CHRNA2 Antibody
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Anti-CHRNA2 Antibody


Anti-CHRNA2 Antibody  的详细介绍
Name: Anti-CHRNA2 Antibody
See all CHRNA2 primary antibodies
Description: Rabbit polyclonal antibody to CHRNA2
Specificity: The antibody detects endogenous levels of total CHRNA2 protein.
Applications: WB, IHC
Reactivity: Human
Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human cholinergic receptor, nicotinic, alpha 2 (neuronal)
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1.9mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Involvement in Disease: Epilepsy, nocturnal frontal lobe, 4: An autosomal dominant focal epilepsy characterized by nocturnal seizures associated with fear sensation, tongue movements, and nocturnal wandering, closely resembling nightmares and sleep walking.
Sequence Similarities: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-2/CHRNA2 sub-subfamily.
Cellular Location: Cell junction > Synapse > Postsynaptic cell membrane. Cell membrane.
Database Links:
  • Entrez Gene: 1135?Human
  • Omim: 118502?Human
  • SwissProt: Q15822?Human
  • Unigene: 57718?Human
    		•
    Synonyms:
  • ACHA2_HUMAN Antibody
  • AChR Antibody
  • Cholinergic receptor nicotinic alpha 2 Antibody
  • Chrna2 Antibody
  • Neuronal acetylcholine receptor protein subunit alpha 2 Antibody
  • Neuronal acetylcholine receptor subunit alpha-2 Antibody
  • Nicotinic Acetylcholine Receptor alpha 2 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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