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Anti-CHRM2 Antibody

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产品名称: Anti-CHRM2 Antibody
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简单介绍

Anti-CHRM2 Antibody


Anti-CHRM2 Antibody  的详细介绍
Name: Anti-CHRM2 Antibody
See all CHRM2 primary antibodies
Description: Goat polyclonal antibody to CHRM2.
Applications: ELISA, WB
Reactivity: Mouse
Immunogen: Synthetic peptide corresponding to Human CHRM2 (internal region).
Sequence: C-QNGDEKQNIVARK
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 µg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol (By similarity).
Sequence Similarities: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM2 sub-subfamily.
Post-Translational Modification: Phosphorylated in response to agonist treatment.
Cellular Location: Cell membrane. Cell junction > Synapse > Postsynaptic cell membrane.

Phosphorylation in response to agonist binding promotes receptor internalization.
Database Links:
  • Entrez Gene: 243764 Mouse
  • SwissProt: Q9ERZ4 Mouse
  • Unigene: 448632 Mouse
    		•
    Synonyms:
  • 7TM receptor Antibody
  • Acetylcholine receptor, muscarinic, 2 Antibody
  • AChR Antibody
  • Acm2 Antibody
  • ACM2_HUMAN Antibody
  • Cholinergic receptor muscarinic 2 Antibody
  • Cholinergic receptor, muscarinic 2, cardiac Antibody
  • Cholinergic receptor, muscarinic 2, isoform a Antibody
  • Cholinergic receptor, muscarinic 2a Antibody
  • CHRM 2 Antibody
  • CHRM2 Antibody
  • chrm2a Antibody
  • CM2 Antibody
  • FLJ43243 Antibody
  • HM 2 Antibody
  • HM2 Antibody
  • M2 Antibody
  • M2 muscarinic receptor Antibody
  • M2-mAChR Antibody
  • MGC120006 Antibody
  • MGC120007 Antibody
  • Muscarinic Acetylcholine Receptor 2 Antibody
  • Muscarinic acetylcholine receptor M2 Antibody
  • Muscarinic M2 receptor Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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