产品资料

Anti-Cerebral 1 (L310) Antibody

如果您对该产品感兴趣的话,可以
产品名称: Anti-Cerebral 1 (L310) Antibody
产品型号:
产品展商: 其它品牌
产品文档: 无相关文档

简单介绍

Anti-Cerebral 1 (L310) Antibody


Anti-Cerebral 1 (L310) Antibody  的详细介绍
Name: Anti-Cerebral 1 (L310) Antibody
See all Cerebral 1 primary antibodies
Description: Rabbit polyclonal antibody to Cerebral 1 (L310)
Specificity: Cerebral 1 (L310) pAb detects endogenous levels of Cerebral 1 protein.
Applications: WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 291-340 of Human Cerebral 1.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 51 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Function: Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.
Sequence Similarities: Belongs to the methyltransferase superfamily. RRP8 family.
Cellular Location: Nucleus > Nucleolus.

Localizes at rDNA locus.
产品留言
标题
联系人
联系电话
内容
验证码
点击换一张
注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

沪公网安备 31011202007337号