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Anti-CENPO Antibody

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产品名称: Anti-CENPO Antibody
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简单介绍

Anti-CENPO Antibody


Anti-CENPO Antibody  的详细介绍
Name: Anti-CENPO Antibody
See all CENPO primary antibodies
Description: Rabbit polyclonal antibody to CENPO
Specificity: The antibody detects endogenous levels of total CENPO protein.
Applications: IHC
Reactivity: Human
Immunogen: Full length fusion protein
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1.8mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Modulates the kinetochore-bound levels of NDC80 complex.
Cellular Location: Nucleus. Chromosome > Centromere. Chromosome > Centromere > Kinetochore.

The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
Database Links:
  • Entrez Gene: 79172?Human
  • Omim: 611504?Human
  • SwissProt: Q9BU64?Human
  • Unigene: 731569?Human
    		•
    Synonyms:
  • CENP-O Antibody
  • CENPO Antibody
  • CENPO_HUMAN Antibody
  • Centromere protein O Antibody
  • ICEN 36 Antibody
  • Interphase centromere complex protein 36 Antibody
  • MCM21R Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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