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Anti-CENPM Antibody

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产品名称: Anti-CENPM Antibody
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简单介绍

Anti-CENPM Antibody


Anti-CENPM Antibody  的详细介绍
Name: Anti-CENPM Antibody
See all CENPM primary antibodies
Description: Rabbit polyclonal antibody to CENPM
Specificity: The antibody detects endogenous levels of total CENPM protein.
Applications: IHC
Dilutions: Immunohistochemistry: 1:100-1:200
Reactivity: Human
Immunogen: Full length fusion protein
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1.6mg / ml
Formulation: Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Storage: Store at -20?C
Function: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres.
Tissue Specificity: Isoform 3 is highly expressed in spleen, and intermediately in heart, prostate and ovary. Isoform 3 is highly expressed in resting CD19 B-cells and B-lineage chronic lymphocytic leukemia (B-CLL) cells and weakly expressed in activated B-cells. Isoform 1 is selectively expressed in activated CD19 cells and weakly in resting CD19 B-cells.
Cellular Location: Nucleus. Cytoplasm. Chromosome > Centromere > Kinetochore.

Nuclear in non-confluent cells and cytoplasmic in confluent or dividing cells (By similarity). Localizes in the kinetochore domain of centromeres.
Synonyms:
  • bK250D10.2 Antibody
  • C22orf18 Antibody
  • CENP M Antibody
  • CENPM Antibody
  • Centromere protein M Antibody
  • ICEN 39 Antibody
  • ICEN39 Antibody
  • Interphase centromere complex protein 39 Antibody
  • MGC861 Antibody
  • OTTHUMP00000028741 Antibody
  • PANE 1 Antibody
  • PANE1 Antibody
  • Proliferation associated nuclear element 1 Antibody
  • Proliferation associated nuclear element protein 1 Antibody
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    Information: Target information shown above is from the UniProt Consortium.
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