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Antibodies
Anti-CDO1 Antibody
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产品名称:
Anti-CDO1 Antibody
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简单介绍
Anti-CDO1
Antibody
Anti-CDO1 Antibody
的详细介绍
Overview
Name:
Anti-CDO1
Antibody
See all CDO1 primary antibodies
Description:
Rabbit polyclonal antibody to CDO1
Specificity:
The antibody detects endogenous levels of total CDO1 protein.
Applications:
IHC
Reactivity:
Human
Immunogen:
Full length fusion protein
Host:
Rabbit
Clonality:
Polyclonal
Conjugate:
Unconjugated
Purification:
Antigen affinity purification.
Concentration:
2mg / ml
Formulation:
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:
Store at -20?C
Target
Function:
Initiates several important metabolic pathways related to pyruvate and several sulfurate compounds including sulfate, hypotaurine and taurine. Critical regulator of cellular cysteine concentrations. Has an important role in maintaining the hepatic concentation of intracellular free cysteine within a proper narrow range.
Tissue Specificity:
Highly expressed in liver and placenta. Low expression in heart, brain and pancreas. Also detected in hepatoblastoma Hep-G2 cells.
Sequence Similarities:
Belongs to the cysteine dioxygenase family.
Post-Translational Modification:
The thioether cross-link between Cys-93 and Tyr-157 plays a structural role through stabilizing the Fe(2+) ion, and prevents the production of highly damaging free hydroxyl radicals by holding the oxygen radical via hydroxyl hydrogen.
Database Links:
Entrez Gene: 1036?Human
Omim: 603943?Human
SwissProt: Q16878?Human
Unigene: 442378?Human
Synonyms:
CDO Antibody
CDO 1 Antibody
CDO I Antibody
CDO-I Antibody
Cdo1 Antibody
CDO1_HUMAN Antibody
CDOI Antibody
Cysteine Dioxygenase Type 1 Antibody
Cysteine dioxygenase type I Antibody
Cytosolic cysteine dioxygenase Antibody
Information:
Target information shown above is from the UniProt Consortium.
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