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Anti-CDKN3 Antibody

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产品名称: Anti-CDKN3 Antibody
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简单介绍

Anti-CDKN3 Antibody


Anti-CDKN3 Antibody  的详细介绍
Name: Anti-CDKN3 Antibody
See all CDKN3 primary antibodies
Description: Rabbit polyclonal antibody to CDKN3
Specificity: The antibody detects endogenous level of total CDKN3 protein.
Applications: WB, IHC, IF
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human CDKN3.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antibodies were purified by affinity purification using immunogen.
Concentration: 1.0mg / ml
Formulation: Supplied at 1.0mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20?C
Function: May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. Dephosphorylates CDK2 at 'Thr-160' in a cyclin-dependent manner.
Involvement in Disease: Hepatocellular carcinoma: A primary malignant neoplasm of epithelial liver cells. The major risk factors for HCC are chronic hepatitis B virus (HBV) infection, chronic hepatitis C virus (HCV) infection, prolonged dietary aflatoxin exposure, alcoholic cirrhosis, and cirrhosis due to other causes.
Sequence Similarities: Belongs to the protein-tyrosine phosphatase family.
Cellular Location: Cytoplasm > Perinuclear region.
Database Links:
  • Entrez Gene: 1033?Human
  • Entrez Gene: 72391?Mouse
  • Entrez Gene: 289993?Rat
  • Omim: 123832?Human
  • SwissProt: Q16667?Human
  • SwissProt: Q810P3?Mouse
  • SwissProt: B2RZ50?Rat
  • Unigene: 84113?Human
  • Unigene: 272394?Mouse
  • Unigene: 107220?Rat
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    Synonyms:
  • CDI1 Antibody
  • Cdk associated protein phosphatase Antibody
  • CDK2 associated dual specificity phosphatase Antibody
  • CDK2-associated dual-specificity phosphatase Antibody
  • CDKN3 Antibody
  • CDKN3_HUMAN Antibody
  • CIP2 Antibody
  • Cyclin dependent kinase inhibitor 3 Antibody
  • Cyclin dependent kinase interacting protein 2 Antibody
  • Cyclin dependent kinase interactor 1 Antibody
  • Cyclin-dependent kinase inhibitor 3 Antibody
  • Cyclin-dependent kinase interactor 1 Antibody
  • Cyclin-dependent kinase-interacting protein 2 Antibody
  • FLJ25787 Antibody
  • KAP Antibody
  • KAP1 Antibody
  • Kinase associated phosphatase Antibody
  • Kinase-associated phosphatase Antibody
  • MGC70625 Antibody
  • OTTHUMP00000178991 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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